Bernd Heiser

Title: Bernd Heiser: Innovator in Chiral Phosphorus Compounds and Isoquinoline Derivatives

Introduction

Bernd Heiser is a notable inventor based in Inzlingen, Germany. He has made significant contributions to the field of chemistry, particularly in the development of chiral phosphorus compounds and isoquinoline derivatives. With a total of 6 patents to his name, Heiser's work has implications for various applications in asymmetric synthesis.

Latest Patents

Heiser's latest patents include innovative advancements in chiral phosphorus compounds. These compounds are characterized by the formula ##STR1##, where R signifies lower alkyl, R.sup.1 signifies phenyl, and R.sup.2 and R.sup.3 signify hydrogen or lower alkoxy. They are suitable for use as catalysts in asymmetric hydrogenations and enantioselective hydrogen displacements in prochiral allylic systems. Another significant patent involves isoquinoline derivatives, detailing a process for their preparation. The compounds of formula IV are obtained by asymmetrically hydrogenating the compounds of formula I, which are derived from isomerizing specific compounds.

Career Highlights

Bernd Heiser is currently associated with Hoffmann-La Roche Inc., a leading company in the pharmaceutical industry. His work at the company has allowed him to focus on innovative research and development in the field of chemistry. Heiser's contributions have been instrumental in advancing the understanding and application of chiral compounds.

Collaborations

Heiser has collaborated with notable colleagues such as Joseph Foricher and Rudolf Schmid. These collaborations have fostered a productive environment for innovation and have led to significant advancements in their respective fields.

Conclusion

In summary, Bernd Heiser is a distinguished inventor whose work in chiral phosphorus compounds and isoquinoline derivatives has made a lasting impact in the field of chemistry. His contributions continue to influence research and development in asymmetric synthesis.