Company Filing History:
Years Active: 2011-2013
Title: Bernardino Mangion: Innovator in Pharmaceutical Chemistry
Introduction
Bernardino Mangion is a notable inventor based in Santa Lucia, Malta. He has made significant contributions to the field of pharmaceutical chemistry, particularly through his innovative work on polymorphic forms of compounds used in medical treatments. With a total of 3 patents to his name, Mangion's inventions have the potential to impact the pharmaceutical industry significantly.
Latest Patents
One of Mangion's latest patents is titled "Polymorphic forms of a 3-pyrrole substituted 2-indolinone." This invention relates to new crystalline polymorphic forms of N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide, commonly known as sunitinib base. The patent includes various forms, such as Form I, Form II, and Form IV, along with processes for preparing these crystalline forms and their pharmaceutically acceptable salts. Another significant patent is for the "Process for preparing a 3-pyrrole substituted 2-indolinone malate salt." This invention focuses on the malic acid salt of N-[2-(diethylamino)ethyl]-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide, which serves as an intermediate for preparing the malic acid salt of sunitinib and related pharmaceutical compositions.
Career Highlights
Throughout his career, Bernardino Mangion has worked with reputable companies in the pharmaceutical sector. Notable among these are Medichem, S.A. and Laboratorio Chimico Internazionale S.p.A. His work in these organizations has allowed him to develop and refine his innovative ideas, contributing to advancements in drug formulation and delivery.
Collaborations
Mangion has collaborated with various professionals in his field, including his coworker Stephen Benedict David Winter. These collaborations have fostered an environment of innovation and creativity, leading to the development of new pharmaceutical solutions.
Conclusion
Bernardino Mangion's contributions to pharmaceutical chemistry through his patents and collaborations highlight his role as an influential inventor in the industry. His work continues to pave the way for advancements in drug development