Company Filing History:
Years Active: 2018-2019
Title: Berenice Alfonso: Innovator in Polynucleotide Detection
Introduction
Berenice Alfonso is a notable inventor based in Fairfax Station, VA (US). She has made significant contributions to the field of molecular biology, particularly in the detection of target polynucleotides. With a total of 2 patents, her work has the potential to advance diagnostic techniques in various applications.
Latest Patents
Berenice Alfonso's latest patents include innovative methods for detecting target polynucleotides. The first patent, titled "Exonuclease Cycling Assay," describes a novel method that involves hybridizing a target polynucleotide with a probe to form a hybrid. This hybrid is then exposed to a 5' exonuclease, which digests the probe and dissociates the target polynucleotide. The process is repeated, and the presence of digested probes indicates the presence of the target polynucleotide.
The second patent, "Polymerase Driven NESA," outlines a method that begins with exposing the target polynucleotide to an initiating oligonucleotide. This oligonucleotide is extended with a complementary sequence, ligated to form a circular oligonucleotide, and then exposed to a DNA polymerase for synthesis. The synthesized DNA is further processed to detect the presence of the target polynucleotide through the cleavage of a probe.
Career Highlights
Berenice Alfonso is affiliated with Georgetown University, where she continues her research and development in molecular biology. Her innovative approaches have garnered attention in the scientific community, contributing to advancements in genetic detection methods.
Collaborations
Throughout her career, Berenice has collaborated with notable colleagues, including Mark Danielsen and Bolor Tumurpurev. These collaborations have enhanced her research efforts and expanded the impact of her inventions.
Conclusion
Berenice Alfonso is a pioneering inventor whose work in polynucleotide detection is shaping the future of molecular diagnostics. Her contributions through her patents reflect her commitment to advancing scientific knowledge and technology.