This inventor holds 1 USPTO granted patent. Top assignee: Ludwig Institute for Cancer Research Limited. Active years: 2024.
Company Filing History:
Years Active: 2024
Title: Innovations in Cancer Treatment by Benoit J Van Den Eynde
Introduction
Benoit J Van Den Eynde is a notable inventor based in Oxford, GB. He has made significant contributions to the field of cancer research, particularly through his innovative patent related to viral vectors. His work aims to enhance cancer treatment methodologies and improve patient outcomes.
Latest Patents
Benoit J Van Den Eynde holds a patent for "Viral vectors encoding cancer/testis antigens for use in a method of prevention or treatment of cancer." This patent involves the use of Chimpanzee adenovirus (ChAd) and MVA virus vectors that contain polynucleotide sequences encoding cancer antigens. These vectors are administered sequentially to a subject along with a suitable adjuvant to achieve a prime boost effect. The polynucleotides are expressed in situ after administration, leading to the production of a MAGEA3/linker/NY-ESO-1 fusion protein and its variants. The approach has shown an improved T cell response, and a synergistic therapeutic strategy involving a triple combination of ChAdOx and MVA vectors, along with a chemotherapeutic agent and checkpoint inhibitor, has demonstrated significant efficacy in depleting myeloid-derived suppressor cells (MDSC) and improving survival time in a mouse model of cancer.
Career Highlights
Benoit J Van Den Eynde is associated with the Ludwig Institute for Cancer Research Limited, where he continues to advance his research in cancer treatment. His innovative approaches have positioned him as a key figure in the ongoing battle against cancer.
Collaborations
Benoit has collaborated with esteemed colleagues such as Carol S Leung and Adrian V S Hill. These partnerships have further enriched his research and contributed to the development of effective cancer therapies.
Conclusion
Benoit J Van Den Eynde's work exemplifies the intersection of innovation and medical research, particularly in the field of cancer treatment. His contributions through patents and collaborations are paving the way for new therapeutic strategies that could significantly impact patient care.