Benny Chih

Title: Benny Chih: Innovator in Neurological Research

Introduction

Benny Chih is a notable inventor based in South San Francisco, CA, who has made significant contributions to the field of neurological research. With a total of two patents to his name, he is recognized for his innovative approaches to understanding and treating neurological disorders.

Latest Patents

Benny Chih's latest patents include groundbreaking work on agonists of TREM2. This application discloses certain antibodies that specifically bind to human TREM2, which is a triggering receptor expressed on myeloid cells. The antibodies act as TREM2 agonists and are designed to bind to the stalk region of intact human TREM2 without interacting with soluble TREM2. These antibodies have shown potential in enhancing the survival of human microglia cells and increasing Aβ plaque formation, which may provide neuroprotective activities. Another significant patent involves oligonucleotides for modulating TMEM106B expression. This invention relates to oligonucleotides that are complementary to TMEM106B and includes pharmaceutical compositions and methods for treating neurological disorders.

Career Highlights

Benny Chih is currently employed at Genentech, Inc., where he continues to advance his research in the field of neurology. His work has been instrumental in developing therapies that target critical pathways involved in neurological disorders.

Collaborations

Benny has collaborated with esteemed colleagues such as Peter Hagedorn and Marianne Lerbech Jensen, contributing to a dynamic research environment that fosters innovation and discovery.

Conclusion

Benny Chih's contributions to neurological research through his patents and collaborations highlight his role as a leading inventor in the field. His work continues to pave the way for advancements in the treatment of neurological disorders.