Philadelphia, PA, United States of America

Benjamin S Szwergold



Average Co-Inventor Count = 4.4

ph-index = 2

Forward Citations = 26(Granted Patents)


Company Filing History:


Years Active: 1993-1999

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2 patents (USPTO):Explore Patents

Title: Innovations of Benjamin S Szwergold

Introduction

Benjamin S Szwergold is a notable inventor based in Philadelphia, PA. He has made significant contributions to the field of diabetes research through his innovative patents. His work focuses on therapeutic interventions aimed at preventing diabetic complications.

Latest Patents

Szwergold holds two patents that highlight his groundbreaking research. The first patent involves compounds and methods for therapeutic intervention in preventing diabetic complications. This invention is based on the discovery of a metabolic pathway where a specific kinase converts fructose-lysine into fructose-lysine-3-phosphate in an ATP-dependent reaction. The resulting fructose-lysine-3-phosphate (FL3P) can lead to the formation of advanced glycation end-product modified proteins (AGE-proteins), which are linked to diabetic complications. His patent discloses a class of compounds that inhibit the action of FL3P kinase, providing therapeutic methods to reduce the formation of AGE-proteins.

The second patent focuses on assessing the risk of diabetes-associated pathological conditions. It involves determining the concentrations of phosphorylated carbohydrates in biological tissues or cells of diabetic patients. Elevated levels of these carbohydrates are associated with an increased risk of developing degenerative complications of diabetes. This method allows for the assessment of a patient's risk for complications and the efficacy of therapeutic interventions.

Career Highlights

Szwergold is affiliated with the Fox Chase Cancer Center, where he continues to advance his research. His work has garnered attention for its potential impact on diabetes treatment and prevention.

Collaborations

He has collaborated with notable colleagues, including Truman R Brown and Francis Kappler, to further his research initiatives.

Conclusion

Benjamin S Szwergold's innovative patents and research contributions are paving the way for new therapeutic approaches in diabetes management. His work exemplifies the importance of scientific innovation in addressing complex health challenges.

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