Location History:
- Ann Arbor, MI (US) (2002)
- New York, NY (US) (1995 - 2003)
Company Filing History:
Years Active: 1995-2003
Title: The Innovative Contributions of Benjamin L Margolis
Introduction
Benjamin L Margolis is a prominent inventor based in New York, NY (US). He has made significant contributions to the field of cancer research, holding a total of 10 patents. His work focuses on the development of methods and compositions for the prevention and treatment of oncogenic disorders, particularly breast cancer.
Latest Patents
One of his latest patents is titled "Prognostic evaluation of cancer." This invention relates to compositions and methods for the prevention, prognostic evaluation, and treatment of oncogenic disorders. It specifically involves a protein tyrosine kinase that can complex with a member of the SH2- and/or SH3-containing family of adaptor proteins. In a preferred embodiment, the protein tyrosine kinase is the receptor protein tyrosine kinase HER2, and the adaptor protein is GRB, forming a HER2/GRB-7 complex.
Another notable patent is the "Expression-cloning method for identifying target proteins for eukaryotic tyrosine kinases and novel target proteins." This invention presents a novel method based on direct expression cloning for identifying target proteins that can bind to and/or serve as substrates for receptor or cytoplasmic tyrosine kinases. It also includes methods for identifying compounds that disrupt the interaction of these novel proteins with the kinases.
Career Highlights
Benjamin L Margolis is affiliated with New York University, where he continues to advance his research in the field of cancer treatment and diagnostics. His innovative approaches have garnered attention and recognition within the scientific community.
Collaborations
Throughout his career, Margolis has collaborated with esteemed colleagues such as Joseph Schlessinger and Edward Y Skolnik. These collaborations have further enriched his research and contributed to the advancement of knowledge in the field.
Conclusion
Benjamin L Margolis is a distinguished inventor whose work has significantly impacted cancer research. His innovative patents and collaborations highlight his commitment to improving cancer treatment and prognostic evaluation.