This inventor holds 2 USPTO granted patents. Top assignee: University of Colorado. Active years: 2013-2021.
Location History:
- Broomfeld, CO (US) (2013)
- Broomfield, CO (US) (2021)
Company Filing History:
Years Active: 2013-2021
Title: Innovations of Benjamin L Barthel
Introduction
Benjamin L Barthel is an accomplished inventor based in Broomfield, CO (US). He has made significant contributions to the field of cancer treatment through his innovative research and development of novel compounds.
Latest Patents
Barthel holds 2 patents that focus on anthracycline prodrugs and methods of making and using them. His first patent involves compounds of the class anthracycline that have been modified to include photo-activated prodrug anthracycline compounds. These compounds are particularly useful in the treatment of cancer. One example composition includes photodoxazolidine, which can be synthesized in two steps from 4,5-dimethoxy-2-nitrobenzyl alcohol and doxazolidine. The process involves the reaction of commercial 4,5-dimethoxyl-2-nitrobenzyl alcohol with p-nitrophenylchloroformate to produce the p-nitrophenyl carbonate of the benzyl alcohol derivative. This carbonate is then reacted with doxazolidine to yield the exemplary photodoxazolidine composition. His second patent provides therapeutically effective compounds for the prevention and treatment of cancer, along with pharmaceutical compositions containing these compounds. It also includes methods of activating a prodrug of these compounds through the administration of a peptide-directed targeting construct that delivers a prodrug-activating enzyme to a target activation site.
Career Highlights
Barthel's work at the University of Colorado has positioned him as a key figure in the development of innovative cancer therapies. His research has the potential to significantly impact the treatment landscape for cancer patients.
Collaborations
He has collaborated with notable colleagues such as Tad H Koch and Glen C Post, contributing to a rich environment of innovation and discovery.
Conclusion
Benjamin L Barthel's contributions to cancer treatment through his innovative patents and research at the University of Colorado highlight his role as a significant inventor in the field. His work continues to pave the way for advancements in therapeutic approaches to cancer.