Company Filing History:
Years Active: 1988-2003
Title: The Innovations of Benjamin D. Hall: Pioneering Virus Antigen Synthesis
Introduction
Benjamin D. Hall, an esteemed inventor based in Bellevue, WA, has made significant contributions to the field of biotechnology. With a portfolio of 7 patents, his most notable work centers around the synthesis of human virus antigens using yeast as a means to advance medical and biological research.
Latest Patents
One of Hall's latest patents, titled "Synthesis of Human Virus Antigens by Yeast," explores the synthesis of Hepatitis B Antigen (HB Ag) in yeast. This innovative approach involves the construction of yeast expression vectors that contain a yeast promoter, known as ADH1. Hall successfully transferred specific regions of the HBV genome encoding for the S-protein into these vectors. His work led to the successful synthesis of HB Ag, which is notably antigenic and reacts with anti-HB Ag antibodies. The yeast-derived product displays similarities to naturally occurring HB Ag particles and highlights a groundbreaking method for synthesizing complex multi-component structures within microorganisms.
Another significant patent by Hall is also focused on the "Synthesis of Human Virus Antigens by Yeast," emphasizing the synthesis of HBsAg in a similar yeast-based system. The implications of his research extend to a deeper understanding of viral structures and potential therapeutic applications.
Career Highlights
Throughout his illustrious career, Benjamin D. Hall has been associated with notable organizations, contributing to advancements in biomedical research. He has worked with the Washington Research Foundation and Genentech, Inc., where he leveraged his expertise to push the boundaries of what is possible in the field of antigen synthesis.
Collaborations
Collaboration has been a key element of Hall's success. He has worked alongside esteemed colleagues such as Gustav Ammerer and Ronald A. Hitzeman. Their combined efforts have fostered an environment of innovation and scientific inquiry, helping to propel new discoveries in the biotechnology sector.
Conclusion
Benjamin D. Hall's groundbreaking work in the synthesis of virus antigens using yeast stands as a testament to his innovative spirit and dedication to scientific advancement. With his impressive portfolio of patents and impactful collaborations, Hall continues to inspire future generations of inventors and researchers in the field of biotechnology. His contributions have not only advanced our understanding of viral structures but also hold potential for future therapeutic developments.
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