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Years Active: 2023
Title: Ben Thuronyi: Innovator in Base Editing Technologies
Introduction
Ben Thuronyi is a notable inventor based in Williamstown, MA (US). He has made significant contributions to the field of genetic engineering, particularly in the development of base editing technologies. His innovative work has led to advancements that enhance the efficiency and specificity of genetic modifications.
Latest Patents
Thuronyi holds a patent for "Methods and compositions for evolving base editors using phage-assisted continuous evolution (PACE)." This patent describes evolved base editors that address deficiencies found in existing technologies. The evolved cytidine base editors, based on APOBEC1, CDA, or AID cytidine deaminase domains, demonstrate increased efficiency and reduced requirements for specific sequence-context at editing sites. This advancement is a result of the phage-assisted continuous evolution (PACE) system.
Career Highlights
Throughout his career, Ben Thuronyi has worked with prestigious institutions such as Harvard College and The Broad Institute, Inc. His work in these organizations has allowed him to collaborate with leading scientists and contribute to groundbreaking research in genetic editing.
Collaborations
Thuronyi has collaborated with prominent researchers, including David R. Liu and Christopher Gerard Wilson. These partnerships have furthered the development of innovative technologies in the field of base editing.
Conclusion
Ben Thuronyi's contributions to the field of genetic engineering, particularly through his patent on evolved base editors, highlight his role as a key innovator. His work continues to influence advancements in genetic modification techniques.