Ben P Peeters

Title: **Innovations of Ben P Peeters: Pioneering Secretory Signal Selection Vectors**

Introduction

Ben P Peeters, an accomplished inventor based in Haren, Netherlands, has made significant contributions to the field of biotechnology. With a notable portfolio comprising two patents, Peeters has focused his research on enhancing the efficiency of extracellular protein synthesis through innovative vector technologies.

Latest Patents

Peeters' latest patents revolve around the development of secretory signal selection vectors designed for improved extracellular protein synthesis. These novel vectors facilitate the identification of secretory signal sequences derived from DNA fragments of unicellular microorganisms. The patented plasmids feature a multiple cloning site complemented by restriction sites in reading frame with a structural gene, allowing for rapid screening of the secreted expression products. Notably, these vectors may optionally integrate a promoter region located upstream from the multiple cloning site. Exemplifying his approach with Bacillus, Peeters has isolated specific secretory signal sequences that enable efficient secretion of proteins into the supernatant, rather than merely to the periplasmic space. This innovative methodology ensures economically high yields of proteins, with the provided secretory sequences demonstrating superiority over previously known alternatives.

Career Highlights

Throughout his tenure at Gist Brocades N.V., Peeters has focused on advancing biotechnological applications with a keen emphasis on protein engineering. His inventive work has far-reaching implications in various industries, potentially improving processes ranging from pharmaceuticals to food production.

Collaborations

As part of his research endeavors, Peeters has collaborated with esteemed colleagues, including Hilde E. Smith and Jan H. Van Ee. Together, they have contributed to a dynamic research environment fostering creative solutions to complex scientific challenges.

Conclusion

Ben P Peeters stands out as a prominent inventor whose innovative work in secretory signal selection vectors has substantial implications for extracellular protein synthesis. With a commitment to excellence and collaboration, Peeters continues to push the boundaries of biotechnological advancements at Gist Brocades N.V. His contributions will undoubtedly play a vital role in shaping the future of protein engineering and related industries.