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Title: Innovations of Behzad Mehrafrooz
Introduction
Behzad Mehrafrooz is an accomplished inventor based in Urbana, Illinois. He has made significant contributions to the field of proteomics through his innovative methods and systems. His work focuses on the linearization and translocation of single protein molecules, which has important implications for scientific research and medical applications.
Latest Patents
Behzad Mehrafrooz holds a patent for a method and system for linearization and translocation of single protein molecules through nanopores. This patent describes a technique for performing single molecule proteomics utilizing a nanopore sensor. The sensor measures the electronic signature of proteins or peptides as they are transported through the nanopore from one chamber to another. The electronic signature is determined by the ionic current over time. The method employs an agent, such as guanidinium chloride, to bind to the nanopore's interior, creating an electroosmotic force that facilitates the stretching and unfolding of proteins during transport. This innovative approach may also induce protein unfolding prior to transport and assist in moving the protein through the nanopore.
Career Highlights
Throughout his career, Behzad Mehrafrooz has worked at prestigious institutions, including Northeastern University and the University of Illinois. His research has garnered attention for its potential to advance the understanding of protein behavior at the molecular level.
Collaborations
Behzad has collaborated with notable colleagues, including Meni Wanunu and Luning Yu. Their combined expertise has contributed to the development of groundbreaking techniques in the field of nanopore technology.
Conclusion
Behzad Mehrafrooz's innovative work in the field of proteomics and nanopore technology highlights his significant contributions to science. His patent for the linearization and translocation of single protein molecules showcases the potential for advancements in molecular research.