Bat Sheva Kerem

Title: Bat Sheva Kerem: Innovator in CFTR Gene Modulation

Introduction

Bat Sheva Kerem is a notable inventor based in Mevaseret Zion, Israel. She has made significant contributions to the field of genetic research, particularly in the modulation of the CFTR gene, which is crucial for understanding cystic fibrosis.

Latest Patents

Kerem holds a patent titled "Restoration of the CFTR function by splicing modulation." This invention provides oligonucleotides capable of binding to and modulating the splicing of the pre-mRNA of the CFTR gene. The patent includes compositions comprising these oligonucleotides and their uses, such as suppressing the inclusion of a cryptic exon between exon 22 and 23 due to the mutation 3849+10Kb C-to-T, optionally in combination with additional CF therapeutics. She has 1 patent to her name.

Career Highlights

Throughout her career, Bat Sheva Kerem has worked with various research institutions, contributing her expertise to advance genetic research. She has been associated with Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. and Splisense Ltd., where she has played a pivotal role in developing innovative solutions for genetic disorders.

Collaborations

Kerem has collaborated with notable colleagues, including Efrat Ozeri-Galai and Yifat Oren, who have contributed to her research endeavors.

Conclusion

Bat Sheva Kerem's work in CFTR gene modulation exemplifies the impact of innovative research on genetic therapies. Her contributions continue to pave the way for advancements in the treatment of cystic fibrosis and related conditions.