Location History:
- London, GB (2002 - 2015)
- Charterhouse Square, GB (2017)
Company Filing History:
2 out of 3 
1 out of 525 
1 out of 1,743 
Years Active: 2002-2024
Title: Bart Vanhaesebroeck: Innovator in Vascular Health
Introduction
Bart Vanhaesebroeck is a notable inventor based in London, GB, recognized for his contributions to the field of vascular health. He holds a total of four patents, showcasing his innovative approach to addressing critical health issues.
Latest Patents
One of his latest patents focuses on the use of PI3KC2B inhibitors for the preservation of vascular endothelial cell barrier integrity. Ischemic conditions are a leading cause of death for both men and women. Ischemia is characterized by reduced blood flow and oxygen to an organ. The re-establishment of blood flow, or reperfusion, and re-oxygenation of the affected area following an ischemic episode is critical to limit irreversible damage. However, reperfusion can also lead to potentially damaging consequences. Increased vascular permeability is an important contributor to edema and tissue damage following ischemic events. In this patent, the inventor demonstrates that genetic inhibition of PI3K-C2β reduces cerebral infarction in two ischemia/reperfusion (I/R) models and improves neurological outcomes. The genetic inhibition stabilizes the blood-brain barrier (BBB) after ischemic stroke and reduces inflammation. Accordingly, the present invention relates to a method for preserving vascular endothelial cell barrier integrity in a patient in need thereof, comprising administering a therapeutically effective amount of a PI3KC2β inhibitor. Another significant patent involves a method for identifying the activation of transferases, providing a means to identify differential activation of a bisubstrate protein modifying enzyme between samples.
Career Highlights
Throughout his career, Bart has worked with several prominent organizations, including Hvivo Services Limited and the Ludwig Institute for Cancer Research Limited. His work in these companies has contributed to advancements in medical research and innovation.
Collaborations
Bart has collaborated with notable colleagues such as Pedro Rodriguez Cutillas and Michael Derek Waterfield, further enhancing his research and development efforts.
Conclusion
Bart Vanhaesebroeck's innovative work in vascular health and his significant patents highlight his commitment to improving medical outcomes for patients. His contributions are vital in the ongoing fight against ischemic conditions and their associated complications.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.