Barry M Heatfield

Title: Barry M Heatfield: Innovator in Non-Inflammatory Collagen Applications

Introduction

Barry M Heatfield is a notable inventor based in Baltimore, MD (US). He has made significant contributions to the field of biomedical materials, particularly through his innovative work on collagen-enzyme conjugates. His research focuses on creating non-inflammatory collagen products that have a wide range of medical applications.

Latest Patents

Barry M Heatfield holds 1 patent for his invention related to collagen-enzyme conjugates that exhibit no inflammatory response. This patent details a method where collagen polymers are rendered non-inflammatory by complexation with alkaline phosphatase. The applications of these non-inflammatory collagen complexes are extensive, including the production of non-inflammatory collagen sutures, collagen soft tissue replacements such as wound and burn coverings, arterial vessel replacements, and collagen drug delivery devices. Additionally, these conjugates can be used for vitreous replacement in ophthalmologic therapy. Gels composed of the collagen-alkaline phosphatase conjugate combined with calcium hydroxide serve as effective agents in endodontic therapy. The structural durability and stabilization of the anti-inflammatory properties of the material are enhanced through crosslinking with glutaraldehyde or other crosslinking agents, which also sterilizes and disinfects the collagen conjugate prior to in-vivo use.

Career Highlights

Throughout his career, Barry M Heatfield has focused on advancing the field of biomedical engineering. His innovative approaches have led to the development of materials that significantly improve patient outcomes in various medical procedures. His work is characterized by a commitment to enhancing the safety and effectiveness of medical treatments.

Collaborations

Barry has collaborated with esteemed colleagues such as Steven R Jefferies and James L Gutmann. These partnerships have fostered a collaborative environment that encourages the exchange of ideas and expertise, further driving innovation in the field.

Conclusion

Barry M Heatfield's contributions to the development of non-inflammatory collagen products represent a significant advancement in biomedical materials. His innovative work continues to impact the medical field positively, providing safer and more effective solutions for various applications.