Barry Kingston Derham

Title: Barry Kingston Derham: Innovator in Protein Stability

Introduction

Barry Kingston Derham is a notable inventor based in Cambridge, GB. He has made significant contributions to the field of protein formulations, holding a total of 4 patents. His work focuses on enhancing the stability of protein compositions, which is crucial for various applications in biotechnology and pharmaceuticals.

Latest Patents

Among his latest patents, one notable invention is the "Stabilized aqueous antibody compositions." This invention provides an aqueous solution comprising an antibody protein at a concentration of at least about 10 mg/mL and an oligomer of ethyleneimine, wherein the number of repeating units of ethyleneimine (n) in the oligomer is in the range of n=2-12. Another significant patent is related to "Protein formulations with increased stability." This invention reveals that the addition of aromatic carboxylate ions can inhibit protein instability caused by aromatic preservatives. The resulting compositions remain stable and suitable for storage at ambient temperatures or lower, even in aqueous form.

Career Highlights

Barry Kingston Derham is associated with Arecor Limited, where he continues to innovate in the field of protein stability. His research has led to advancements that benefit the pharmaceutical industry by improving the shelf life and efficacy of protein-based drugs.

Collaborations

Throughout his career, Barry has collaborated with notable colleagues such as Jan Jezek and Guy Casy. These partnerships have fostered a collaborative environment that enhances the development of innovative solutions in protein formulations.

Conclusion

Barry Kingston Derham is a distinguished inventor whose work in protein stability has made a significant impact in biotechnology. His patents reflect a commitment to advancing the field and improving the efficacy of protein-based therapies.