Company Filing History:
Years Active: 1997-1999
Title: Innovations of Barry C. Cole
Introduction
Barry C. Cole is an accomplished inventor based in Sandy, Utah. He has made significant contributions to the field of biotechnology, particularly in the study of Mycoplasma arthritidis. With a total of three patents to his name, Cole's work has implications for understanding autoimmune diseases and developing diagnostic methods.
Latest Patents
Cole's latest patents include a method for purifying Mycoplasma arthritidis T-cell mitogen (MAM). This method achieves electrophoretic and sequence homogeneity, allowing for the determination of the N-terminal 54 amino acids of MAM. A synthetic peptide derived from this sequence has been shown to inhibit MAM-induced cell proliferation in vitro. Additionally, he has molecularly cloned the gene encoding the superantigen MAM, modifying it for expression in standard systems. His work also includes a method for diagnosing rheumatoid arthritis using recombinant MAM protein in an ELISA assay.
Career Highlights
Barry C. Cole is affiliated with the University of Utah Research Foundation, where he continues to advance research in his field. His innovative approaches have led to significant findings that enhance our understanding of immune responses and disease mechanisms.
Collaborations
Cole has collaborated with notable colleagues, including Curtis L. Atkin and Arnold R. Oliphant, contributing to a rich environment of research and innovation.
Conclusion
Barry C. Cole's contributions to biotechnology and his innovative patents reflect his dedication to advancing medical science. His work not only enhances our understanding of Mycoplasma arthritidis but also paves the way for new diagnostic methods in autoimmune diseases.