Barbara Wetzer

Title: Barbara Wetzer: Innovator in Acid-Sensitive Compounds

Introduction

Barbara Wetzer is a prominent inventor based in Paris, France. She has made significant contributions to the field of chemistry, particularly in the development of acid-sensitive compounds. Her innovative work has the potential to impact various applications in the biomedical field.

Latest Patents

Barbara Wetzer holds a patent for "Acid-sensitive compounds, their preparation and uses." This patent describes novel acid-sensitive compounds that comprise a cyclic ortho-ester, which is acid-sensitive, along with their salts. These compounds include at least one hydrophilic substituent and are useful for forming conjugates, such as liposomes, complexes, and nanoparticles, with biologically active substances. They can release these substances into cellular tissues or compartments with acidic pH. Additionally, they serve as nonionic surfactants for stabilizing particles that encapsulate biologically active substances, which can then be destabilized in acidic environments. Furthermore, these compounds can act as vectors covalently linked to therapeutic molecules, facilitating their release into acidic cellular tissues or compartments.

Career Highlights

Barbara Wetzer is currently associated with Gencell, S.A., where she continues to advance her research and development efforts. Her work is characterized by a strong focus on innovative solutions that address complex challenges in the field of biomedicine.

Collaborations

Barbara collaborates with esteemed colleagues, including Michel Bessodes and Christophe Masson. Their combined expertise enhances the research and development initiatives at Gencell, S.A.

Conclusion

Barbara Wetzer's contributions to the field of acid-sensitive compounds exemplify her innovative spirit and dedication to advancing biomedical applications. Her work not only showcases her expertise but also highlights the importance of collaboration in scientific research.