Barbara Mui

Title: Barbara Mui: Innovator in Lipid Nanoparticle Formulations

Introduction

Barbara Mui is a prominent inventor based in Vancouver, Canada. She has made significant contributions to the field of lipid nanoparticle formulations, holding three patents that showcase her innovative work. Her inventions focus on improving the delivery of therapeutic agents and enhancing cellular transfection methods.

Latest Patents

One of Barbara Mui's latest patents involves improved formulations of lipid nanoparticles. These formulations are designed for the effective delivery of therapeutic agents. Additionally, she has developed compositions for the introduction of polyanionic materials into cells. This invention provides methods that utilize mixtures of cationic compounds and neutral lipids, typically formulated as liposomes. The cationic compounds are quaternary ammonium compounds with long chain alkyl groups, at least one of which is unsaturated. The methods for transfecting cells involve creating a polyanionic material-liposome complex and then contacting this complex with the target cells.

Career Highlights

Throughout her career, Barbara Mui has worked with notable companies such as Inex Pharmaceuticals Corporation and Acuitas Therapeutics, Inc. Her work in these organizations has contributed to advancements in drug delivery systems and therapeutic applications.

Collaborations

Barbara has collaborated with esteemed colleagues, including Steven Michial Ansell and Michael J Hope. These partnerships have further enriched her research and development efforts in the field of lipid nanoparticles.

Conclusion

Barbara Mui is a trailblazer in the realm of lipid nanoparticle formulations, with a focus on enhancing therapeutic delivery and cellular transfection. Her innovative patents and collaborations reflect her commitment to advancing medical technology.