Barbara Imperiali

Title: Barbara Imperiali: Innovator in Glycan-Binding Proteins

Introduction

Barbara Imperiali is a prominent inventor based in Cambridge, MA (US), known for her significant contributions to the field of glycan-binding proteins. With a total of 12 patents to her name, she has made remarkable advancements in the understanding and application of these proteins.

Latest Patents

Her latest patents focus on glycan-binding proteins and related compositions and methods. These patents describe proteins that include scaffolds based on easily evolvable DNA-binding proteins, which possess binding sites capable of specifically binding to mono- or disaccharides. This includes monosaccharide-binding determinants, disaccharide-binding determinants, and more complex carbohydrates. In certain aspects, a protein may be generated starting from a small DNA-binding protein, such as Sso7d. The applications of these glycan-binding proteins are vast, encompassing enzyme-linked immunosorbent assays (ELISAs), glycan characterization, cell selection, flow cytometry, histology, imaging, arrays, affinity purification, enzyme-linked visualization, and binding to targets for pharmaceutical purposes.

Career Highlights

Barbara has worked with prestigious institutions such as the Massachusetts Institute of Technology and Boston University. Her work has significantly impacted the scientific community, particularly in the area of glycan-binding proteins.

Collaborations

Some of her notable coworkers include Melissa D Shults and Elvedin Lukovic, who have collaborated with her on various projects.

Conclusion

Barbara Imperiali continues to be a leading figure in the field of glycan-binding proteins, contributing to innovative research and applications that have the potential to transform various scientific and medical fields.