Location History:
- East Lansing, MI (US) (1990)
- Waterloo, CA (1997 - 1999)
Company Filing History:
Years Active: 1990-1999
Title: Barbara A Moffatt: Innovator in RNA Polymerase Research
Introduction
Barbara A Moffatt is a distinguished inventor based in Waterloo, Canada. She has made significant contributions to the field of molecular biology, particularly in the cloning and expression of bacteriophage T7 RNA polymerase. With a total of 3 patents, her work has advanced the understanding and application of RNA synthesis.
Latest Patents
Moffatt's latest patents focus on the cloning and expression of the gene for bacteriophage T7 RNA polymerase. This application describes a method to clone a functional gene for T7 RNA polymerase, which is crucial for synthesizing large amounts of RNA both in vivo and in vitro. The active enzyme produced from the cloned gene is highly efficient in transcribing DNA and selective for long promoter sequences. This innovation allows for the production of specific RNA from complex mixtures of DNAs, enhancing the capabilities of RNA synthesis systems.
Career Highlights
Throughout her career, Barbara A Moffatt has worked with notable organizations such as Associated Universities, Inc. and Brookhaven Science Associates, LLC. Her expertise in molecular biology has positioned her as a key figure in the research community.
Collaborations
Moffatt has collaborated with esteemed colleagues, including F William Studier and Parichehre Davanloo. These partnerships have furthered her research and contributed to advancements in the field.
Conclusion
Barbara A Moffatt's innovative work in RNA polymerase research has had a lasting impact on molecular biology. Her patents and collaborations reflect her dedication to advancing scientific knowledge and technology.