Awadhesh K Mishra

Title: Innovations of Awadhesh K Mishra

Introduction

Awadhesh K Mishra is a notable inventor based in California, recognized for his contributions to the field of pharmaceutical formulations. With a total of nine patents to his name, he has made significant advancements in drug delivery systems and sterilization processes.

Latest Patents

One of his latest patents is titled "Thermoprotected compositions and process for terminal steam sterilization of microparticle preparations." This invention involves compositions of submicron- to micron-sized particles of water-insoluble biologically active substances that are stabilized by thermoprotecting agents. These compositions can be terminally steam sterilized without any significant increase in mean particle size, displaying markedly reduced heat-induced coagulation, flocculation, or particle size growth during the sterilization process.

Another significant patent is the "Process for preparing a rapidly dispersing solid drug dosage form." This invention describes a rapidly dispersing solid dry therapeutic dosage form comprised of a water-insoluble compound existing as a nanometer or micrometer particulate solid. The particulate solid is surface stabilized by the presence of at least one phospholipid, allowing it to disperse throughout a bulking matrix. When introduced into an aqueous environment, the bulking matrix dissolves within less than two minutes, releasing the water-insoluble particulate solid in an unaggregated state.

Career Highlights

Awadhesh K Mishra has worked with various companies, including Jagotec AG, where he has contributed to innovative pharmaceutical solutions. His work has focused on enhancing drug delivery methods and improving the stability of pharmaceutical compositions.

Collaborations

Throughout his career, he has collaborated with notable professionals in the field, including Michael G Vachon and Gary William Pace. These collaborations have further enriched his research and development efforts.

Conclusion

Awadhesh K Mishra's innovative work in pharmaceutical formulations and drug delivery systems has made a significant impact in the industry. His patents reflect a commitment to advancing medical technology and improving patient outcomes.