Avrameas Stratis

Title: Avrameas Stratis: Innovator in Nucleic Acid Detection

Introduction

Avrameas Stratis is a notable inventor based in Paris, France. He has made significant contributions to the field of molecular biology, particularly in the development of innovative probes for nucleic acid detection. His work has implications for various applications in research and diagnostics.

Latest Patents

Stratis holds a patent for a "Non-radioactive labelled single-stranded probe, method for manufacturing." This invention relates to a new probe designed for detecting a specified nucleic acid sequence. The probe consists of recombinant DNA containing an insert that is complementary to the nucleic acid sequence to be detected. Notably, the thymine groups in the DNA are replaced by 5-bromouracil groups. The method for manufacturing this probe involves culturing cell hosts, particularly E. coli, which are auxotrophic for thymine in a medium with a limiting concentration of thymine and containing 5-bromouracil. After incubation, the probe is recovered from the bacterial cells.

Career Highlights

Throughout his career, Stratis has worked with prestigious institutions such as the Institute Pasteur and the Centre National de la Recherche Scientifique. His research has contributed to advancements in the understanding and detection of nucleic acids, which are crucial for various scientific and medical applications.

Collaborations

Stratis has collaborated with notable colleagues, including Hiroshi Sakamoto and Francois Traincard. These collaborations have further enriched his research and innovation in the field.

Conclusion

Avrameas Stratis is a distinguished inventor whose work in nucleic acid detection has paved the way for new methodologies in molecular biology. His contributions continue to influence research and diagnostics in significant ways.