August A Specht

Title: August A Specht: Innovator in Mass Spectrometry

Introduction

August A Specht is a notable inventor based in Pleasanton, CA (US). He has made significant contributions to the field of mass spectrometry, particularly in the analysis of proteins and polypeptides. With a total of 3 patents, his work has advanced the methodologies used in this critical area of research.

Latest Patents

Specht's latest patents include innovative methods for mass spectrometry of mixtures of proteins or polypeptides using proton transfer reaction. One of his methods involves making an extract of a biological sample and repeatedly choosing a respective one of a plurality of pre-determined protein or polypeptide analyte compounds. This process includes introducing a portion of the extract into an electrospray ionization source, generating positive ions, isolating subsets of ion species, and generating a mass spectrum to identify the presence or absence of the compound. Another patent focuses on applications of ion-ion reaction chemistry, utilizing proton transfer reactions to simplify complex mixture analysis and improve resolution and sensitivity for large proteins.

Career Highlights

August A Specht is currently associated with Thermo Finnigan LLC, where he continues to innovate in the field of mass spectrometry. His work has been instrumental in enhancing the capabilities of mass spectrometers, making them more effective for complex biological analyses.

Collaborations

Specht has collaborated with notable colleagues such as James L Stephenson, Jr and John E P Syka. These collaborations have further enriched his research and development efforts in mass spectrometry.

Conclusion

August A Specht's contributions to mass spectrometry have significantly impacted the analysis of biological samples. His innovative methods and collaborations continue to push the boundaries of what is possible in this field.