Atsushi Shimada

Title: Atsushi Shimada and Hyperthermostable Enzyme Innovation.

Introduction

Atsushi Shimada is an inventor associated with Shiga, Japan, and Takara Shuzo Co., Inc. His patent work concerns a hyperthermostable beta-galactosidase gene derived from *Pyrococcus furiosus* and the enzyme encoded by that gene.

Latest Patents

The provided information lists 1 patent for Shimada: “Hyperthermostable β-galactosidase gene, enzyme encoded thereby, and …”. The invention describes isolated gene sequences, including examples identified as SEQ ID NO. 2 and SEQ ID NO. 4, as well as related DNA sequences that hybridize with them. It also outlines methods for cloning the gene using the sequences or portions of them as probes or primers, and for producing the enzyme by culturing a transformant containing a plasmid with the gene. A particularly preferred gene encodes an SDS-resistant, hyperthermostable beta-galactosidase.

Career Highlights

The available details connect Shimada’s inventive work with Takara Shuzo Co., Inc. His listed patent focuses on genetic methods and enzyme production, with potential relevance to biotechnology processes that require enzymes capable of withstanding high temperatures.

Collaborations

Miki Odate and Nobuto Koyama are identified as Shimada’s coworkers in connection with the supplied information. The details provided do not specify their individual roles in the patent.

Conclusion

Atsushi Shimada’s listed patent documents work on cloning and producing a heat-resistant beta-galactosidase from *Pyrococcus furiosus*, highlighting an application of genetic engineering to thermostable enzyme development.