Ibaraki, Japan

Asuka Ose


Average Co-Inventor Count = 2.3

ph-index = 3

Forward Citations = 48(Granted Patents)


Company Filing History:

goldMedal9 out of 947 
 
Chugai Seiyaku Kabushiki Kaisha
 patents
silverMedal1 out of 832,680 
Other
 patents
where one patent can have more than one assignee

Years Active: 2004-2014

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9 patents (USPTO):Explore Patents

Title: Asuka Ose: Innovator in Transporter Genes and Fetal Polypeptides

Introduction

Asuka Ose is a prominent inventor based in Ibaraki, Japan. She has made significant contributions to the field of biotechnology, particularly in the cloning of novel transporter genes and the isolation of fetal polypeptides. With a total of 9 patents to her name, Ose's work has implications for drug development and cancer treatment.

Latest Patents

One of her latest patents involves the cloning of transporter genes OATP-B, C, D, and E. These four novel transporter genes were successfully identified through screening based on the human OATP transporter gene sequence. The transporters play a crucial role in the development of drugs by facilitating the transport of biological substances and various drugs. Additionally, it was discovered that these transporter genes possess single nucleotide polymorphisms (SNPs). Gene diagnosis based on these polymorphisms allows for the assessment of drug therapy efficacy. Another significant patent pertains to the isolation of novel fetal genes, fls353 and fls485, from human fetal liver-derived cDNAs. These genes are specifically expressed in fetal tissues, which are believed to contain a high number of undifferentiated and actively proliferating cells. High expression levels of these genes have also been observed in various cancer cells, making them valuable tools for developing tumor treatment drugs.

Career Highlights

Throughout her career, Asuka Ose has worked with notable companies, including Chugai Seiyaku Kabushiki Kaisha. Her innovative research has positioned her as a key figure in the biotechnology sector, contributing to advancements in drug development and genetic research.

Collaborations

Asuka Ose has collaborated with esteemed colleagues, including Jun-Ichi Nezu and Akira Tsuji. These partnerships have further enhanced her research and innovation in the field.

Conclusion

Asuka Ose's contributions to biotechnology through her patents and research have made a significant impact on drug development and cancer treatment. Her work continues to inspire advancements in the field, showcasing the importance of innovation in science.

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