Asiri Ediriwickrema

Title: Innovations of Asiri Ediriwickrema

Introduction

Asiri Ediriwickrema is a prominent inventor based in Cary, NC (US). He has made significant contributions to the field of materials science, particularly in the development of innovative polymer-coated particles. With a total of 9 patents to his name, his work has implications in various applications, including medical and cosmetic fields.

Latest Patents

Among his latest patents are the "Hyperbranched polyglycerol-coated particles and methods of making and using thereof" and "Core-shell particles and methods of making and using thereof." These patents describe core-shell particles where the core is formed of hydrophobic materials, while the shell consists of hyperbranched polyglycerol (HPG). The HPG coating can be modified to enhance the properties of the particles. Unmodified HPG coatings provide stealth properties that resist non-specific protein absorption and improve circulation in the bloodstream. Additionally, the hydroxyl groups on the HPG coating can be chemically modified to create functional groups that adhere the particles to tissues, cells, or extracellular materials.

Another notable patent is the "Topical formulation of hyperbranched polymer-coated particles." This patent details core-shell particles with a hydrophobic core and a shell made of hyperbranched polymers (HP). The HP can be covalently bound to the core materials or coated onto them. The HP coating can also be modified to adjust particle properties, with unmodified HP coatings resisting non-specific protein absorption. The hydroxyl groups on the HP coating can be chemically altered to form functional groups that interact with tissue, allowing the particles to adhere effectively.

Career Highlights

Asiri Ediriwickrema is affiliated with Yale University, where he continues to advance his research in polymer science and its applications. His innovative work has garnered attention in both academic and industrial circles, contributing to the development of new materials that can be utilized in various fields.

Collaborations

He has collaborated with notable colleagues, including Yang Deng and William Mark Saltzman, further enhancing the impact of his research through teamwork and shared expertise.

Conclusion

Asiri Ediriwickrema's contributions to the field of polymer science through his patents and research at Yale University highlight his role as a leading inventor. His innovative approaches to creating functional polymer-coated particles have the potential to revolutionize applications in medicine and cosmetics.