Ashok Kumar Jha

Title: Innovations of Ashok Kumar Jha in HDAC Inhibition

Introduction

Ashok Kumar Jha is a notable inventor based in Telangana, India. He has made significant contributions to the field of medicinal chemistry, particularly in the development of selective HDAC inhibitors. His work focuses on creating compounds that have the potential to impact therapeutic strategies for various diseases.

Latest Patents

One of Ashok Kumar Jha's key patents is titled "Indole (sulfomyl) n-hydroxy benzamide derivatives as selective HDAC inhibitors." This patent describes sulfonyl hydroxamic acid compounds characterized by a general formula where Ring A and B can be aryl, heteroaryl, cycloalkyl, or fused groups. The substituents R can include a variety of functional groups such as hydrogen, alkoxy, aryloxy, hydroxy, and more. These compounds are recognized for their role as HDAC inhibitors, which are crucial in the regulation of gene expression and have implications in cancer therapy.

Career Highlights

Ashok Kumar Jha is affiliated with the Council of Scientific & Industrial Research, where he continues to advance research in his field. His innovative approach to drug design and development has garnered attention in the scientific community.

Collaborations

He has collaborated with notable colleagues, including Chandrasekhar Srivari and Prathama Satyendra Mainkar, to further enhance the research and development of new therapeutic agents.

Conclusion

Ashok Kumar Jha's contributions to the field of HDAC inhibitors exemplify the importance of innovation in medicinal chemistry. His work not only advances scientific knowledge but also holds promise for future therapeutic applications.