Asa Ben Hur

Title: Asa Ben Hur: Innovator in Gene Expression Analysis

Introduction

Asa Ben Hur is a notable inventor based in Seattle, WA, who has made significant contributions to the field of gene expression analysis. With a total of two patents to his name, he has developed innovative methods that enhance the understanding of biological data.

Latest Patents

One of Asa Ben Hur's latest patents is titled "Identification of co-regulation patterns by unsupervised cluster analysis of gene expression data." This method provides a way to perform unsupervised clustering of gene expression data to identify co-regulation patterns. The clustering algorithm randomly divides the data into k different subsets and measures the similarity between pairs of data points within these subsets. It assigns a score to the pairs based on their similarity, with the highest similarity yielding the highest correlation score. A distribution of these scores is plotted for each k, allowing researchers to determine the number of co-regulation patterns based on the highest value of k that maintains a concentrated distribution near the highest correlation score.

Another significant patent is "Model selection for cluster data analysis." This method offers a model selection technique for determining the number of clusters or the parameters of a clustering algorithm. The algorithm compares the similarity between pairs of clustering runs on sub-samples or other perturbations of the data. High pairwise similarities indicate that the clustering represents a stable pattern in the data. This method is applicable to any clustering algorithm and can also detect a lack of structure. Asa Ben Hur has demonstrated results on both artificial and real data using a hierarchical clustering algorithm.

Career Highlights

Asa Ben Hur is currently associated with Health Discovery Corporation, where he continues to apply his expertise in data analysis and clustering techniques. His work has been instrumental in advancing the understanding of gene expression and its implications in various biological contexts.

Collaborations

Asa has collaborated with notable colleagues in his field, including Isabelle Guyon and André Elisseeff. These collaborations have further enriched his research and contributed to the development of innovative methodologies in gene expression analysis.

Conclusion

Asa Ben Hur is a pioneering inventor whose work in gene expression analysis has led to significant advancements in the field. His innovative patents and contributions continue to influence research and applications in biological data analysis.