Location History:
- Stow, MA (US) (1984)
- Hopedale, MA (US) (1995)
Company Filing History:
Years Active: 1984-1995
Title: Arthur Myles: Innovator in Nucleotide Detection and Functionalized Liposomes
Introduction
Arthur Myles is a notable inventor based in Hopedale, MA (US). He has made significant contributions to the field of biotechnology, particularly in the areas of nucleotide detection and liposome functionalization. With a total of 2 patents, Myles has developed innovative methods that enhance the capabilities of genetic analysis and immunoassays.
Latest Patents
Myles' latest patents include a method for detecting a nucleotide at a specific location within a strand of DNA. This novel technique utilizes an exonucleolytic agent that retains a labeled nucleotide in a primer when there is a match between the test nucleotide on the DNA strand and the complementary nucleotide on the primer. The presence or absence of the test nucleotide can be established by determining whether the label is preserved or lost following the reaction. Another significant patent involves the use of phosphotriester intermediates for the preparation of functionalized liposomes. This method forms an analyte-functionalized liposome for use in immunoassay techniques, employing a phosphotriester intermediate of a phospholipid derivatized with the desired analyte. The resulting liposomes are functionalized on their outer surface with the analyte and carry an enzyme marker.
Career Highlights
Arthur Myles is currently associated with Collaborative Research, Inc., where he continues to push the boundaries of scientific research and innovation. His work has been instrumental in advancing methodologies that are crucial for genetic testing and immunological applications.
Collaborations
Myles has collaborated with esteemed colleagues such as Ronald W. Davis and Say-Jong Law. These partnerships have fostered an environment of innovation and have contributed to the successful development of his patented technologies.
Conclusion
Arthur Myles stands out as a prominent inventor whose work in nucleotide detection and functionalized liposomes has the potential to significantly impact the fields of genetics and immunology. His contributions continue to pave the way for advancements in biotechnology.