Company Filing History:
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Years Active: 1993-2003
Title: The Innovative Mind of Arno F. Spatola: A Pioneer in Antimicrobial Peptide Research
Introduction: Arno F. Spatola is a distinguished inventor based in Louisville, KY, whose contributions to the field of peptide chemistry have led to the development of cutting-edge antimicrobial agents. With a remarkable portfolio of six patents, Spatola's work primarily focuses on cyclic peptide mixtures, advancing the methodologies for peptide synthesis and their potential applications in screening for new therapeutics.
Latest Patents: Among his latest patents, Spatola has developed two significant methodologies: one related to antimicrobial agents through cyclic peptide mixtures via side chain or backbone attachment and another detailing a method of preparing these cyclic peptide mixtures using solid phase synthesis. His innovative approach involves the attachment of amino acids to a solid support, enabling the mimicking of solution cyclization procedures with linear peptides. Utilizing Boc chemistry for peptide synthesis, he has refined the cyclization process with uronium reagents and strong acids for deprotection and cleavage. This methodology not only creates cyclic peptide libraries but also features the versatility to include at least twenty different amino acids at each position, making significant strides in the field.
Career Highlights: Spatola's impressive career includes key positions at Research Corporation Technologies, Inc. and the University of Louisville, where he actively contributed to the research and development of peptide-based innovations. His work demonstrates a commitment to advancing biomedical science and addressing critical health challenges through innovative chemistry.
Collaborations: Throughout his career, Arno F. Spatola has collaborated with notable colleagues such as Robert D. Gray and Krzysztof Darlak, further enriching his research and expanding the impact of his discoveries in the scientific community.
Conclusion: Arno F. Spatola stands out as a pioneering inventor whose work on cyclic peptide mixtures has opened new avenues for antimicrobial agent development. His innovative methodologies not only enhance the field of peptide synthesis but also demonstrate the significant potential of his research in solving complex health issues. With continuous contributions to science and technology, he remains a prominent figure in the realm of peptide chemistry.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.