Aran Paulus

Title: Aran Paulus: Innovator in Protein Quantification

Introduction

Aran Paulus is a notable inventor based in San Jose, California, recognized for his contributions to the field of protein quantification. With a total of eight patents to his name, he has made significant advancements in methods that enhance the accuracy and efficiency of protein analysis.

Latest Patents

One of his latest patents focuses on stain-free protein quantification and normalization. This innovative method utilizes haloalkylated tryptophan fluorescence to quantify and normalize complex protein samples, which often contain over 1,000 distinct proteins from various sources. The process involves treating these samples with a halo-substituted organic compound that reacts with tryptophan residues, resulting in fluorescent products. By irradiating the samples with ultraviolet light, the emitted fluorescent signals can be detected and quantified, providing comparative values for total protein content across different samples. This technique addresses the variability in tryptophan levels among proteins and corrects for inconsistencies in sample dilution, loading, and transfer.

Career Highlights

Throughout his career, Aran Paulus has worked with prominent organizations such as Bio-Rad Laboratories, Inc. and Technion Research & Development Foundation Limited. His experience in these companies has contributed to his expertise in protein analysis and innovation.

Collaborations

Aran has collaborated with notable colleagues, including Anton Posch and Steve Freeby, further enhancing his work in the field of protein quantification.

Conclusion

Aran Paulus stands out as an influential inventor in the realm of protein quantification, with his innovative methods paving the way for advancements in scientific research and applications. His contributions continue to impact the field positively.