Company Filing History:
1 out of 3 
2 out of 832,718 Years Active: 2019-2024
Title: Aprile L Pilon-Clayton: Innovator in Secretoglobin Proteins
Introduction
Aprile L Pilon-Clayton is a notable inventor based in Rockville, MD (US), recognized for his contributions to the field of biochemistry and protein modification. With a total of four patents to his name, he has made significant strides in the development of novel therapeutic compositions.
Latest Patents
One of his latest patents focuses on the modification and compositions of human secretoglobin proteins. This innovation involves generating novel compositions of recombinant human CC10 protein through chemical modifications in vitro. The resulting synthetic preparations contain isoforms of chemically modified rhCC10, characterized by enhanced or altered biological properties compared to the unmodified protein. These preparations have potential applications in identifying and characterizing naturally occurring isoforms of native CC10 protein from biological samples, ultimately aiding in the measurement of new CC10-based biomarkers for assessing patient disease status. Additionally, these novel isoforms may be utilized in treating various medical conditions, including respiratory, autoimmune, and inflammatory diseases.
Another significant patent involves compositions and methods of using secretoglobins to protect the glycocalyx through interactions with heparan sulfate proteoglycan proteins. This patent outlines SCGB-based preparations and their applications in medical, veterinary, and cosmetic fields. The glycocalyx serves as a protective layer surrounding cells, regulating nutrient passage and modifying cell signaling. By binding to and interacting with heparan sulfate proteoglycan proteins, secretoglobins can modulate cellular responses to external factors, enhancing the protective functions of the glycocalyx.
Career Highlights
Throughout his career, Aprile L Pilon-Clayton has worked with various organizations, including Apc Research Assets, LLC. His innovative work has positioned him as a key figure in the field of protein research and therapeutic development.
Collaborations
He has collaborated with notable individuals in his field, including Melissa E Winn and Humcha K Hariprakasha, contributing to the advancement of research in secretoglobins and their applications.
Conclusion
Aprile L Pilon-Clayton's work in the modification of secretoglobin proteins represents a significant advancement in biochemistry, with promising implications for medical treatments and diagnostics. His innovative patents reflect a commitment to enhancing therapeutic options for various health conditions.
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