Location History:
- Grave, NL (1987)
- Spaarndam, NL (1991 - 2000)
Company Filing History:
4 out of 28 
1 out of 4 
1 out of 71 Years Active: 1987-2000
Title: The Innovations of Antonius J Berns
Introduction
Antonius J Berns is a notable inventor based in Spaarndam, Netherlands. He has made significant contributions to the field of biotechnology, particularly in the development of transgenic animals and vaccines. With a total of seven patents to his name, Berns has demonstrated a commitment to advancing scientific knowledge and practical applications in his area of expertise.
Latest Patents
Berns' latest patents include groundbreaking inventions such as transgenic non-human animals that are depleted in a mature lymphocytic cell type. This invention involves transgenic mice characterized by a substantial depletion of a specific lymphocytic cell type, achieved through a transgene contained in the precursor stem cell of the targeted cell type. The transgene encodes a lymphatic polypeptide variant that inhibits the maturation of the lymphocytic cell type. Another significant patent involves a mutant pseudorabies virus, which is not found in nature. This virus has a genome containing mutations in the protein kinase gene region and/or in the 28K gene region, introduced through genetic engineering techniques. The invention also encompasses vaccines containing this modified pseudorabies virus, which are crucial for veterinary medicine.
Career Highlights
Throughout his career, Berns has worked with prominent organizations such as Genpharm International, Inc. and the Centraal Diergeneeskundig Instituut. His work in these institutions has allowed him to collaborate with leading experts in the field and contribute to significant advancements in animal health and biotechnology.
Collaborations
Berns has collaborated with notable colleagues, including Paulus J Krimpenfort and Arnold Leonard Gielkens. These partnerships have facilitated the exchange of ideas and expertise, further enhancing the impact of his inventions.
Conclusion
Antonius J Berns is a distinguished inventor whose work has significantly influenced the fields of biotechnology and veterinary medicine. His innovative patents and collaborations reflect his dedication to advancing scientific research and practical applications.