Antonio De Miranda

Title: The Innovative Contributions of Antonio De Miranda

Introduction

Antonio De Miranda is a notable inventor based in São Paulo, Brazil, recognized for his significant contributions to the field of biotechnology. With a portfolio comprising two patents, De Miranda has focused his research on developing innovative solutions for contraceptive methods and peptide antagonists.

Latest Patents

De Miranda's latest patents reflect his expertise and commitment to advancing reproductive health. One of his inventions details an active agent with contraceptive properties, derived from a peptide fragment of venom. This peptide encompasses the amino acid sequence SEQ ID NO 2 or sequences that exhibit at least 85% similarity, achievable through chemical synthesis or recombinant DNA technologies. Additionally, he has developed a pharmaceutical contraceptive composition that comprises this peptide and one or more pharmaceutically acceptable vehicles. The implications of this invention are significant, as the peptide fragment and its corresponding pharmaceutical compositions are designed to serve as effective contraceptive and spermicide agents.

Another patent pertains to improved corticotropin-releasing factor (CRF) peptide antagonists. This work presents a unique formula where specific modifications to the peptide structure enhance its efficacy. The specific antagonists disclosed include variations like (cyclo 20-23) [D-Phe^12, Lys^23, Nle^21,38]rCRF(12-41) and (cyclo 20-23) [D-Phe^12, Cys^20, Cys^23, Nle^21,38]rCRF(12-41), showcasing De Miranda's innovative approach in the pharmaceutical landscape.

Career Highlights

Throughout his career, Antonio De Miranda has collaborated with leading research institutions, including the Salk Institute for Biological Studies and Universidad De La Frontera. His work has not only contributed to scientific knowledge but has also aimed at practical applications that benefit society.

Collaborations

De Miranda has worked alongside distinguished colleagues such as Wylie W. Vale, Jr. and Jean E. Rivier. These collaborations have undoubtedly enriched his research experience and expanded the horizons of his innovative endeavors.

Conclusion

Antonio De Miranda stands out as a remarkable inventor whose contributions to biotechnology, particularly in contraceptive methods and peptide antagonists, reveal his dedication to improving health outcomes. His patents signify not just innovation but also the potential for practical applications that could aid many individuals. As he continues his work, the impact of De Miranda's inventions can be anticipated to grow, underscoring the importance of inventors in advancing science and technology.