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For the Inventor, By the Inventor

Horni Pocernice, Czechia

Antonin Holy

USPTO Granted Patents = 12

Average Co-Inventor Count = 2.7

ph-index = 10

Forward Citations = 498(Granted Patents)


Location History:

  • Trebesovska, CZ (1988)
  • Prague, CZ (1980 - 1992)
  • Horni Pocernice, CZ (1992 - 1999)
  • Praha, CZ (1989 - 2000)

Company Filing History:

goldMedal7 out of 242 
 
Ceskoslovenska Akademie Ved
 patents
silverMedal5 out of 22 
 
Institute of Organic Chemistry and Biochemistry of the Academy of
 patents
bronzeMedal4 out of 21 
 
Rega Stichting, V.z.w.
 patents
4. 3 out of 16 
 
Stichting Rega Vzw
 patents
5. 1 out of 1 
 
Rega Institut
 patent
where one patent can have more than one assignee

Years Active: 1980-2000

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12 patents (USPTO):Explore Patents
1. 6057305 - Antiretroviral enantiomeric nucleotide analogs (2000-05-02),
2. 5869467 - 9-(2-phosphonylmethoxyethyl) guanine (1999-02-09),
3. 5733896 - N-(3-fluoro-2-phosphonylmethoxypropyl) derivatives of purine and (1998-03-31),
4. 5641763 - N-phosphonylmethoxyalkyl derivatives of pyrimdine and purine bases and a (1997-06-24),
5. 5352786 - Di(2-propyl)esters of (1994-10-04),
6. 5142051 - N-phosphonylmethoxyalkyl derivatives of pyrimidine and purine bases and (1992-08-25),
7. 5130427 - (2R)-2-[di(2-propyl)phosphonylmethoxy]-3-p-to (1992-07-14),
8. 4808716 - 9-(phosponylmethoxyalkyl) adenines, the method of preparation and (1989-02-28),
9. 4724233 - Therapeutical application of phosphonylmethoxyalkyl adenines (1988-02-09),
10. 4659825 - Isomeric O-phosphonylmethyl derivatives of enantiomeric and racemic (1987-04-21),
11. 4605658 - Antivirally active adenine derivatives (1986-08-12),
12. 4230708 - Therapeutic application of (S) -or (RS)-9-(2, 3-dihydroxypropyl) adenine (1980-10-28),

Title: Antonin Holy: Innovator in Antiviral Nucleotide Analogues

Introduction

Antonin Holy is a notable inventor based in Horni Pocernice, Czech Republic. He has made significant contributions to the field of antiviral pharmaceuticals, holding a total of 12 patents. His work primarily focuses on the development of nucleotide analogs that are effective in treating retroviral infections.

Latest Patents

Among his latest patents, one notable invention is related to antiretroviral enantiomeric nucleotide analogs. This invention involves resolved enantiomers that are useful in antiviral pharmaceutical compositions aimed at treating retroviral infections. Another significant patent is for 9-(2-phosphonylmethoxyethyl) guanine, which addresses the technical problem of using new nucleotide analogues as biologically active compounds. This invention includes derivatives of pyrimidine and purine bases that exhibit marked antiviral activity or can be transformed into active compounds through chemical processes.

Career Highlights

Throughout his career, Antonin Holy has worked with esteemed institutions such as the Czech Academy of Sciences and the Institute of Organic Chemistry and Biochemistry of the Academy of Sciences. His research has led to advancements in the field of antiviral treatments, showcasing his dedication to improving public health through innovative solutions.

Collaborations

Antonin Holy has collaborated with notable researchers, including Erik D De Clercq and Ivan Rosenberg. These partnerships have contributed to the development of his groundbreaking inventions and have furthered research in antiviral therapies.

Conclusion

Antonin Holy's contributions to the field of antiviral pharmaceuticals through his innovative nucleotide analogs have made a significant impact. His work continues to inspire advancements in the treatment of retroviral infections.

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