Company Filing History:
Years Active: 1992-2003
Title: Anton J Berns: Innovator in Gene Targeting Technologies
Introduction
Anton J Berns is a prominent inventor based in Spaarndam, Netherlands. He has made significant contributions to the field of genetic engineering, particularly in the area of gene targeting in animal cells. With a total of five patents to his name, Berns has established himself as a key figure in advancing genetic modification techniques.
Latest Patents
Berns' latest patents include innovative methods for high-efficiency gene targeting in mouse embryonic stem cells. The first patent outlines a process that involves constructing a DNA molecule containing desired sequence modifications, which is substantially isogenic with the DNA in the cell genome. This method includes introducing the targeting DNA construct into the cell through various techniques such as microinjection, electroporation, transfection, or calcium phosphate precipitation. The goal is to select cells where the desired sequence modifications have been successfully integrated into the genome via homologous recombination. Another patent focuses on gene targeting in animal cells using isogenic DNA constructs, emphasizing similar methodologies for genome modification.
Career Highlights
Throughout his career, Anton J Berns has worked with notable companies in the biotechnology sector, including Genpharm International, Inc. and Pharming B.V. His work has significantly impacted the development of gene targeting technologies, paving the way for advancements in genetic research and therapeutic applications.
Collaborations
Berns has collaborated with esteemed colleagues such as Els Robanus Maandag and Hein Te Riele. These partnerships have contributed to the success of his research and the development of innovative genetic engineering techniques.
Conclusion
Anton J Berns is a distinguished inventor whose work in gene targeting has transformed the landscape of genetic engineering. His patents and collaborations reflect his commitment to advancing scientific knowledge and technology in this critical field.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.