Edmonton, Canada

Antoine A Noujaim

USPTO Granted Patents = 18 

 


Average Co-Inventor Count = 3.6

ph-index = 5

Forward Citations = 91(Granted Patents)


Company Filing History:


Years Active: 2000-2014

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18 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Antoine A Noujaim

Introduction

Antoine A Noujaim, based in Edmonton, Canada, is a notable inventor with an impressive portfolio of 18 patents. His work primarily focuses on advanced therapeutic strategies, particularly in the realms of antigenic compositions and the targeted delivery of nucleic acids. Noujaim's innovative approach addresses significant challenges in immunotherapy and genetic medicine.

Latest Patents

Noujaim's latest patents showcase his pioneering efforts in the field. One notable patent describes "Antigenic compositions and use of same in the targeted delivery of nucleic acids." This patent outlines methods for delivering therapeutic nucleic acids to target cells using a chimeric antigen designed to encapsulate and transport nucleic acid molecules. The unique feature of this chimeric antigen is its three domains: a nucleic acid interaction domain, a target binding domain, and an immune response domain. This multi-functional approach enhances the internalization of therapeutic agents via receptor-mediated endocytosis, and can be particularly effective in applications such as overcoming host tolerance to viruses and providing immunostimulation.

Additionally, Noujaim has developed compositions for "Chimeric antigens for eliciting an immune response." This patent highlights methods to stimulate immune responses against antigens perceived as 'self' by the body. By presenting a chimeric antigen containing an immune response domain and a host-targeting domain composed of a xenotypic antibody fragment, Noujaim's approach enhances the immune system's ability to recognize and respond to such antigens. As a result, this method promotes a comprehensive humoral and cellular immune response, showcasing the potential for significant advancements in immunotherapies.

Career Highlights

Noujaim has built a distinguished career, contributing to significant advancements in biotherapeutics. His work at companies such as Altarex Corp. and Paladin Labs Inc. underscores his expertise in drug development and immunology. Throughout his career, he has demonstrated a commitment to exploring innovative solutions to complex medical problems.

Collaborations

Collaborating with talented colleagues has been crucial to Noujaim's success. Notable coworkers include Ragupathy Madiyalakan and Rajan George, who have worked alongside him in various research endeavors. These collaborations have fostered a productive environment for innovation and have significantly contributed to the advancement of their shared goals in medical technology.

Conclusion

Antoine A Noujaim's contributions to the fields of immunology and gene therapy are significant, as evidenced by his 18 patents. His innovative strategies for targeted nucleic acid delivery and immune response elicitation position him as a leading figure in the quest for advanced therapeutic solutions. With a solid foundation based on collaboration and expertise, Noujaim continues to pave the way for future innovations in medicine.

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