Anthony T Dore, Jr

Title: The Innovations of Anthony T Dore, Jr.

Introduction

Anthony T Dore, Jr. is a prominent inventor based in Tarrytown, NY (US). He has made significant contributions to the field of biomedical research, particularly in the development of humanized models for studying interleukin-6 (IL-6) and its receptor. With a total of nine patents to his name, Dore's work has the potential to advance therapeutic strategies for various diseases.

Latest Patents

Dore's latest patents focus on the creation of humanized IL-6 and IL-6 receptor mice. These innovations describe methods for replacing endogenous mouse IL-6 and/or IL-6 receptor genes with human equivalents. The patents detail mice that have a replacement at the endogenous IL-6Rα locus with human ectodomain-encoding sequences. Additionally, they include mice that possess a human IL-6 gene regulated by mouse IL-6 regulatory elements, as well as those that replace mouse IL-6-encoding sequences with human IL-6-encoding sequences at the endogenous mouse IL-6 locus.

Career Highlights

Dore is currently employed at Regeneron Pharmaceuticals, Inc., where he continues to push the boundaries of scientific research. His work has been instrumental in developing innovative models that can be used to better understand the role of IL-6 in various biological processes and diseases.

Collaborations

Some of Dore's notable coworkers include Li-Hsien Wang and Sean Stevens. Their collaborative efforts contribute to the advancement of research in the field of immunology and therapeutic development.

Conclusion

Anthony T Dore, Jr. is a distinguished inventor whose work in creating humanized IL-6 and IL-6 receptor mice has significant implications for biomedical research. His contributions continue to pave the way for new therapeutic approaches in treating diseases related to IL-6.