North Andover, MA, United States of America

Anthony J Laccetti

USPTO Granted Patents = 11 

Average Co-Inventor Count = 5.0

ph-index = 8

Forward Citations = 163(Granted Patents)


Location History:

  • New York, NY (US) (1987)
  • North Andover, MA (US) (1994 - 1999)

Company Filing History:


Years Active: 1987-1999

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11 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Anthony J Laccetti

Introduction

Anthony J Laccetti is a notable inventor based in North Andover, MA (US), recognized for his significant contributions to the field of biomedical engineering. With a total of 11 patents to his name, Laccetti has made remarkable advancements, particularly in the development of blood substitutes.

Latest Patents

Among his latest patents is a groundbreaking method for producing a stable polymerized hemoglobin blood-substitute. This innovative method involves mixing blood with an anticoagulant to create a blood solution, followed by washing the red blood cells and separating them from white blood cells. The process includes disrupting the red blood cells to release hemoglobin, which is then treated through high-performance liquid chromatography to create a hemoglobin eluate. This eluate undergoes deoxygenation and is treated with a sulfhydryl compound to stabilize the deoxygenated hemoglobin solution. Finally, a cross-linking agent is added to initiate a polymerization reaction, resulting in a physiologically acceptable polymerized hemoglobin blood-substitute. Another significant patent involves a method for separating unmodified hemoglobin from cross-linked hemoglobin in a hemoglobin solution, utilizing a dissociating agent to form hemoglobin dimers while retaining the cross-linked hemoglobin.

Career Highlights

Laccetti has worked with prominent companies such as Biopure Corporation and W.R. Grace & Co. His experience in these organizations has contributed to his expertise in the field and has facilitated his innovative work in blood substitutes.

Collaborations

Throughout his career, Laccetti has collaborated with notable individuals, including William Richard Light and Maria S Gawryl. These partnerships have likely enhanced his research and development efforts.

Conclusion

Anthony J Laccetti's contributions to the field of biomedical engineering, particularly in the development of blood substitutes, highlight his innovative spirit and dedication to improving medical solutions. His patents reflect a commitment to advancing healthcare technology and addressing critical needs in blood transfusion alternatives.

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