Anthony G Dilella

Title: Innovations by Anthony G Dilella

Introduction

Anthony G Dilella is a notable inventor based in Houston, TX (US). He has made significant contributions to the field of genetics, particularly in the detection of mutations related to phenylalanine hydroxylase genes. His work has implications for diagnosing conditions such as phenylketonuria (PKU).

Latest Patents

Dilella holds 1 patent for his innovative methods for the identification of mutations in the human phenylalanine. This patent discloses a method for detecting mutations in phenylalanine hydroxylase genes. The method can be utilized for identifying PKU affected individuals, PKU heterozygotes, and normal individuals. Additionally, the patent includes synthesized oligonucleotides designed to detect the first mutations identified in the human phenylalanine hydroxylase gene. These probes have base pair mismatches with genomic DNA, which aids in diagnosing normal and mutant phenylalanine hydroxylase genes. Importantly, this method allows for the detection of the genetic trait PKU without requiring a prior family history of the condition.

Career Highlights

Anthony G Dilella is associated with the Howard Hughes Medical Institute, where he continues to advance research in genetics. His work is characterized by a commitment to improving diagnostic methods for genetic disorders.

Collaborations

Dilella has collaborated with Savio L Woo, contributing to the advancement of genetic research and innovation.

Conclusion

Anthony G Dilella's contributions to the field of genetics, particularly through his patent on detecting mutations in phenylalanine hydroxylase genes, highlight his role as an influential inventor. His work continues to impact the diagnosis and understanding of genetic conditions.