Company Filing History:
10 out of 6,958 
2 out of 27 
1 out of 3,288 Years Active: 1999-2008
Title: **The Innovative Contributions of Anne-Marie Light Mettus**
Introduction
Anne-Marie Light Mettus is a prominent inventor based in Feasterville, Pennsylvania, known for her significant contributions to biotechnology and genetic engineering. With a remarkable portfolio of 13 patents, she has focused her research on DNA probes and insecticidal polypeptides, showcasing her commitment to innovation in the life sciences.
Latest Patents
Among her most recent patents, one notable invention pertains to "DNA probes useful in detecting δ-endotoxin-encoding sequences and uses thereof." This inventive work discloses novel DNA probes designed to detect nucleic acid sequences encoding a unique Lepidopteran- and Coleopteran-active δ-endotoxin polypeptide. Furthermore, it includes methods and kits involving these cutting-edge DNA probes, thereby advancing detection techniques in molecular biology.
Another key patent by Mettus is titled "Methods for generating lepidopteran-toxic polypeptides." This innovation outlines novel synthetically modified nucleic acid segments encoding δ-endotoxins with insecticidal activity specifically targeting lepidopteran insects. The patent further discusses the methods for producing these modified proteins, along with techniques for recombinant expression and transformation in suitable host cells. Additionally, it reveals methods for altering specific loop regions in crystal proteins, aimed at enhancing insecticidal potency, which is crucial for agricultural applications.
Career Highlights
Throughout her career, Mettus has collaborated with leading companies in the field, including Monsanto Technology LLC and Ecogen, Inc. Her work has been instrumental in developing agricultural innovations that leverage genetic engineering to improve pest resistance in crops.
Collaborations
Anne-Marie has had the privilege of working alongside distinguished colleagues such as James Arthur Baum and Amy Jelen Gilmer. This collaboration has allowed her to blend her expertise with other innovative minds, furthering advancements in biotechnological research.
Conclusion
The impact of Anne-Marie Light Mettus on the field of biotechnology cannot be understated. With her innovative patents and collaborative spirit, she is a key figure in the ongoing development of genetic engineering technologies. Her work not only enhances our understanding of biological processes but also paves the way for sustainable agricultural practices and pest management solutions.