Anne K Robinson

Title: Anne K Robinson: Innovator in Proteolytic Enzymes

Introduction

Anne K Robinson is a notable inventor based in Philadelphia, PA (US). She has made significant contributions to the field of biochemistry, particularly in the study of proteolytic enzymes derived from hyperthermophilic bacteria. With a total of 2 patents, her work has implications for various industrial applications.

Latest Patents

Robinson's latest patents focus on the discovery of proteolytic enzymes from Pyrococcus furiosus. These cell-free extracts exhibit remarkably high levels of proteolytic activity, as evidenced by the hydrolysis of azocasein. Notably, the loss in activity was only 30% after incubation for 24 hours at 98°C, with a half-life of proteolytic activity at that temperature being approximately 60 hours. Furthermore, extracts incubated at 98°C in 1% sodium dodecyl sulfate (SDS) for 24 hours yielded an SDS-resistant protease with a temperature optimum of at least 100°C. The enzyme retained at least 40% of its activity when tested at 98°C in the presence of various denaturing agents. The protease was classified as a metalloprotease through inhibitor studies, demonstrating trypsin-like cleavage with additional activities.

Career Highlights

Anne K Robinson is affiliated with The Johns Hopkins University, where she continues her research and innovation in the field of biochemistry. Her work has garnered attention for its potential applications in various industries, including pharmaceuticals and biotechnology.

Collaborations

Some of her notable coworkers include Robert M Kelly and Ilse I Blumentals, who have contributed to her research endeavors.

Conclusion

Anne K Robinson's innovative work in the field of proteolytic enzymes showcases her significant contributions to science and technology. Her patents reflect a commitment to advancing our understanding of biochemistry and its applications.