Company Filing History:
Years Active: 1989
Title: Innovations of Anne E DeVaux
Introduction
Anne E DeVaux is a notable inventor based in Marina Del Rey, California. She has made significant contributions to the field of peptide sequencing through her innovative methods. With one patent to her name, her work has implications for advancements in biochemistry and molecular biology.
Latest Patents
Anne E DeVaux holds a patent for a method of thioacylation peptide sequencing with alcoholysis. This sequencing method exploits the thioacylation degradation of polypeptides and proteins. The process involves the reaction of the N-terminal amino acid of a polypeptide with an excess of a thioacylating reagent. After allowing sufficient time for quantitative coupling and removal of excess reagent, the N-thioacyl polypeptide undergoes cleavage by acid. This cleavage yields a 2-substituted-5(4H)-thiazolinone of the N-terminal amino acid. The subsequent addition of a large excess of an aliphatic primary or secondary alcohol results in the formation of the corresponding N-thioacyl amino acid ester. This stable compound is suitable for chromatographic separation and subsequent detection by contemporary methods of high-pressure liquid chromatography.
Career Highlights
Anne E DeVaux is associated with Bio-affinity Systems, Inc., where she continues to contribute to innovative research and development. Her work has positioned her as a key figure in her field, particularly in peptide sequencing technologies.
Collaborations
Some of her notable coworkers include Mark L Stolowitz and Beth A Paape. Their collaborative efforts have further enhanced the research environment at Bio-affinity Systems, Inc.
Conclusion
Anne E DeVaux's contributions to peptide sequencing through her innovative methods highlight her role as a significant inventor in the field. Her work continues to influence advancements in biochemistry and molecular biology.