This inventor holds 2 USPTO granted patents. Top assignee: Calgene Corporation. Active years: 1988-1991.
Company Filing History:
Years Active: 1988-1991
Title: The Innovative Contributions of Anne Crossway
Introduction
Anne Crossway is a prominent inventor based in Davis, CA (US). She has made significant contributions to the field of biotechnology, particularly in the areas of DNA and RNA detection and plant cell microinjection techniques. With a total of 2 patents, her work has advanced the capabilities of genetic analysis and plant transformation.
Latest Patents
Anne's latest patents include a "Microassay for detection of DNA and RNA" and a "Plant cell microinjection technique." The microassay patent describes a novel hybridization diagnostic technique that employs micromanipulation of cells for the detection of DNA or RNA. This method utilizes cellular suspensions, where the nucleic acid is purified through microextraction using liquid media with differential solubilization properties. The nucleic acid is then retained in an aqueous microdrop, allowing for conventional assay methods with nucleic acid probes.
The plant cell microinjection technique patent outlines methods for injecting macromolecules into plant protoplasts. This technique involves using a holding pipette to immobilize the protoplast while an injection pipette delivers the macromolecule. To ensure the protoplasts are not damaged, they are cultured for 1 to 5 days prior to injection, allowing for partial regeneration of the cell wall. This method enables targeted injection into specific compartments of the cell and is particularly useful for transforming plant protoplasts with exogenous genes.
Career Highlights
Anne Crossway is currently associated with Calgene Corporation, where she continues to innovate in the field of biotechnology. Her work has not only contributed to scientific advancements but has also paved the way for practical applications in genetic engineering and diagnostics.
Collaborations
Throughout her career, Anne has collaborated with notable colleagues, including Daniel Facciotti and Catherine M. Houck. These collaborations have further enriched her research and development efforts.
Conclusion
Anne Crossway's contributions to biotechnology through her patents and work at Calgene Corporation highlight her role as a leading inventor in her field. Her innovative techniques in DNA and RNA detection, as well as plant cell microinjection, continue to influence advancements in genetic research and applications.