This inventor holds 1 USPTO granted patent. Top assignees: Assistance Publique - Hopitaux De Paris (Aphp), Fondation Imagine, National Institute of Health and Medical Research. Active years: 2024.
Company Filing History:
1 out of 77 
1 out of 15 
1 out of 1,853 
Years Active: 2024
Title: The Innovative Contributions of Inventor Anne Agnès Rotig
Introduction
Anne Agnès Rotig, an accomplished inventor based in Paris, France, has made significant strides in the field of medical research, particularly concerning neurodegenerative diseases. He holds a notable patent aimed at improving treatment and predicting therapeutic responses for patients suffering from Friedreich ataxia, a debilitating condition caused by genetic mutations.
Latest Patents
Rotig's patent, titled "Treatment and prediction of therapeutic responses in patients suffering from Friedreich ataxia," addresses the underlying causes of this disorder, which stem from a GAA repeat expansion in the FXN gene. This gene encodes frataxin, a mitochondrial protein essential for the assembly of iron-sulfur complexes. The patent reveals critical insights into the mechanisms of iron accumulation in the brain and heart of affected patients and outlines potential therapeutic strategies using molecules such as artesunate, dichloroacetate, and Coenzyme-A, which enhance transferrin receptor palmitoylation and may improve patient outcomes.
Career Highlights
Throughout his career, Anne Agnès Rotig has collaborated with prestigious research institutions, including the Institut National de la Santé et de la Recherche Médicale (Inserm) and Fondation Imagine. His work has significantly advanced the understanding of Friedreich ataxia and has the potential to lead to new treatment paradigms that could change the lives of those impacted by this condition.
Collaborations
In his research endeavors, Rotig has teamed up with esteemed colleagues such as Arnold Munnich and Floriane Petit. This collaborative effort has fostered a rich environment of innovation and has contributed to the successful development of his patent, underscoring the importance of teamwork in scientific discovery.
Conclusion
Anne Agnès Rotig's innovative contributions to the field of medicine, particularly in the treatment of Friedreich ataxia, demonstrate the critical role of inventors in advancing health solutions. His patented methods mark a significant step forward in understanding and potentially reversing the effects of this challenging condition, promising hope for many patients and their families.