Company Filing History:
8 out of 30 
1 out of 6 Years Active: 2012-2019
Title: Annamari Heiskanen: Innovator in Glycoprotein Production
Introduction
Annamari Heiskanen is a prominent inventor based in Helsinki, Finland. She has made significant contributions to the field of biotechnology, particularly in the production of glycoproteins. With a total of eight patents to her name, her work has advanced the understanding and application of glycosylation in recombinant proteins.
Latest Patents
One of her latest patents focuses on the production of glycoproteins with mammalian-like N-glycans in filamentous fungi. This invention relates to compositions and methods that enable the production of recombinant glycoproteins in filamentous fungal cells. The key feature of this invention is that at least 90% of the total neutral N-glycans of the produced recombinant glycoprotein are mammalian-like N-glycans. The invention provides a filamentous fungal cell that includes specific mutations to reduce or eliminate endogenous protease activity, along with polynucleotides that enhance glycoprotein production.
Another notable patent describes a method for evaluating cell populations. This invention identifies specific sialylated structures present on human stem cells and their derived cell populations. It aims to control the status of stem cells by monitoring changes in sialylation, thereby preventing contamination of biological materials. The invention also introduces novel stem cells with specifically altered glycosylation.
Career Highlights
Annamari has worked with several organizations, including Glykos Finland Oy and the Finnish Red Cross Blood Service. Her experience in these companies has allowed her to apply her innovative ideas in practical settings, contributing to advancements in biotechnology.
Collaborations
Throughout her career, Annamari has collaborated with notable colleagues such as Jari Natunen and Tero Satomaa. These partnerships have fostered a collaborative environment that enhances research and development in her field.
Conclusion
Annamari Heiskanen is a trailblazer in the field of glycoprotein production, with a strong portfolio of patents that reflect her innovative spirit. Her contributions continue to impact the biotechnology landscape, paving the way for future advancements.