Company Filing History:
1 out of 47 
1 out of 11 Years Active: 2003
Title: Anna De Martis: Innovator in Ciliary Neurotrophic Factor Research
Introduction
Anna De Martis is a prominent inventor based in Rome, Italy, known for her significant contributions to the field of neurobiology. With a total of two patents, her work focuses on innovative solutions for the treatment of diseases and disorders related to motor neurons and obesity.
Latest Patents
Anna's latest patents include a variant of ciliary neurotrophic factor (CNTF) and DNA encoding the variant. The first patent addresses CNTF variants that exhibit enhanced receptor selectivity, which are beneficial for treating motor neuron diseases and muscle degenerative conditions. This invention specifically highlights the improved therapeutic properties of these variants, demonstrating a reduced ability to elicit biological effects through soluble CNTFR, while retaining their efficacy in activating membrane-bound neuronal CNTF receptors. Additionally, Anna's second patent explores the use of human CNTF and its mutants for developing drugs aimed at treating obesity and associated conditions such as hyperglycemia. The results from her research indicate a notable anti-obesity effect when utilizing these activators.
Career Highlights
Throughout her career, Anna De Martis has worked with notable research institutions, including the Istituto di Ricerche di Biologia Molecolare P. Angeletti. Her extensive research efforts in this institute have contributed greatly to the understanding of neurotrophic factors and their implications in pharmacological developments.
Collaborations
Anna has collaborated with several distinguished colleagues, including Isabelle Gloaguen and Annalise Di Marco. These partnerships have enriched her research, leading to innovative breakthroughs in the molecular biology of ciliary neurotrophic factors.
Conclusion
Anna De Martis's inventive spirit and commitment to advancing biomedical science place her at the forefront of research in neurobiology. With her patents offering new avenues for treatment, her contributions not only enhance academic understanding but also pave the way for practical applications in medicine.