The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2003
Filed:
Jul. 19, 1999
Applicant:
Inventors:
Gennaro Ciliberto, Rome, IT;
Patrizia Costa, Rome, IT;
Giacomo Paonessa, Rome, IT;
Domenico Lazzaro, Rome, IT;
Isabelle Gloaguen, Scoppito L'Aquila, IT;
Annalise Di Marco, Rieti, IT;
Anna De Martis, Rome, IT;
Ralph Laufer, Rome, IT;
Riccardo Cortese, Rome, IT;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/02 ; A01N 3/718 ; A61K 3/818 ; A61K 3/824 ; A61K 3/827 ;
U.S. Cl.
CPC ...
A61F 2/02 ; A01N 3/718 ; A61K 3/818 ; A61K 3/824 ; A61K 3/827 ;
Abstract
The present invention refers to the use of hCNTF (human ciliary neurotrophic factor), mutants thereof or other molecules that activate the CNTF receptor, for the preparation of drugs for the treatment of obesity and associated disease, for example hyperglycemia. FIG. shows the anti-obesity effect of hCNTF and leptin on body weight (left panels) and on food intake (right panels) in genetically obese mice and in mice with diet-induced obesity (DIO).