Location History:
- Palo Alto, CA (US) (1991 - 1999)
- Portola Valley, CA (US) (1999)
Company Filing History:
Years Active: 1991-1999
Title: Ann Tsukamoto: Pioneering Innovations in Hematopoietic Stem Cell Research
Introduction
Ann Tsukamoto is a distinguished inventor known for her significant contributions to the field of hematopoietic stem cell research. Based in Palo Alto, California, she holds a total of seven patents that reflect her innovative approach to gene therapy and stem cell treatment. Her work has the potential to transform the landscape of medical treatments for various diseases.
Latest Patents
Among her latest patents, Tsukamoto has developed methods for optimizing gene transfer into hematopoietic stem cells (HSCs). This method involves contacting the cells with hydroxyurea prior to gene transfer, which induces HSCs in the G0 phase into an active cell cycle. This innovation is particularly useful for treating patients with diseases that can be addressed through gene therapy or involve hematopoietic cells. Additionally, she has created a method to enhance the efficacy of bone marrow transplantation by administering hydroxyurea to increase HSC yields. Another notable patent involves the provision of human hematopoietic stem cells, which are separated from dedicated cells and maintained in an appropriate growth medium. This patent also includes methods for assaying the stem cells' capability to produce members of each hematopoietic lineage, as well as a method for treating humans by implanting a cellular composition comprising over 90% human hematopoietic stem cells.
Career Highlights
Throughout her career, Ann Tsukamoto has worked with notable companies such as Systemix, Inc. and Boco Silicon Valley, Inc. Her innovative research has positioned her as a leader in the field of stem cell therapy, contributing to advancements that could significantly improve patient outcomes.
Collaborations
Tsukamoto has collaborated with esteemed colleagues, including Irving L. Weissman and Charles M. Baum. These partnerships have further enriched her research and expanded the impact of her inventions in the scientific community.
Conclusion
Ann Tsukamoto's pioneering work in hematopoietic stem cell research and gene therapy exemplifies the power of innovation in medicine. Her patents and collaborations continue to pave the way for advancements that hold promise for treating various diseases effectively.